# The Missing Piece of the COVID Puzzle Live Trading News is an independent financial media publication. Masthead: Live Trading News. Parent: Knightsbridge Group. Product cousin: KXCO (kxco.ai). Coverage: markets, policy, AI, quantum, blockchain, FX, biotech, ASEAN. New stories are signed ML-DSA-65 and anchored on Armature L1; articles published before the platform launch are not signed. Nothing on the site is investment advice. Canonical HTML: https://www.livetradingnews.com/the-missing-piece-of-the-covid-puzzle Last modified: 2021-10-28 --- By Paul Ebeling · 2021-10-28 Tags: health, Health, puzzle, immune, Paul Ebeling, niacin, Coronavirus, Covid, Knightsbridge Insights, Covid19, VirusCasedemic, Living, imm Signed: no (published before platform launch). Nothing in this article is investment advice. #COVID #immune #VirusCasedemic #puzzle #Niacin #health *"There is a need to note the importance of vitamin B, as it plays a Key role in cell functioning, energy metabolism and proper immune function*"-- Paul Ebeling - B vitamins may play an important role in COVID-19 prevention and treatment, according to 2 recent papers - Based on B vitamins’ effects on your immune system, immune-competence and red blood cells, which help fight infection, supplementation may be a useful adjunct to other prevention and treatment strategies - B vitamins can influence several COVID-19-specific disease processes, including viral replication and invasion, cytokine storm induction, adaptive immunity and hypercoagulability - Niacin appears to be particularly important. According to 1 published paper, there appears to be a causative link between low niacin status and SARS-CoV-2 infection - SARS-CoV-2’s ability to invade your body is dependent on calcium signaling, which in turn is dependent on the presence of NAADP, which is formed from niacin. NAADP-dependent calcium signaling is responsible both for the inhibition of viral entry into cells and driving the virus out of already infected cells. In the paper: *"Sufficient Niacin Supply: The Missing Puzzle Piece to COVID-19 and Beyond?" *focuses specifically on niacin (B3), raising the question of whether this vitamin might actually be a Key player in the COVID-19 disease process. As noted in the abstract: *"Definitive antiviral properties are evidenced for niacin, i.e., nicotinic acid (NA), as coronavirus disease 2019 (COVID-19) therapy for both disease recovery and prevention, to the level that reversal or progression of its pathology follows as an intrinsic function of NA supply.* "*This detailed investigation provides a thorough disentanglement of how the downstream inflammatory propagation of ensuing severe acute respiratory virus 2 (SARS-CoV-2) infection is entirely prohibited or reversed upstream out the body to expeditiously restore health with well-tolerated dynamic supplementation of sufficient NA (i.e. 1-3 grams per day)."* Notably, niacin has also been shown to: - Reduce the replication of a number of viruses, including vaccinia virus, human immunodeficiency virus, enteroviruses and hepatitis B virus - Reduce neutrophil infiltration - Have anti-inflammatory effect in patients with ventilator-induced lung injury. As a "*health restorative therapy*" for those diagnosed with SARS-CoV-2, they recommend starting with a dose of 500 milligrams of immediate-release niacin, 2 to 3X a day, ideally within the 1st 48 hrs of symptom onset. As your flush response lessens, increase your dose to 1,000 mg, 2 to 3X a day with food. Eat healthy, Be healthy, Live lively --- This Markdown mirrors https://www.livetradingnews.com/the-missing-piece-of-the-covid-puzzle. The HTML page is canonical. Site index for AI clients: https://www.livetradingnews.com/llms.txt